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Pastitsio (Greek Lasagna): The Ultimate Cozy Fall Dinner You’ll Keep Craving

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Let’s get one thing straight: Pastitsio is not your average lasagna. It’s richer. It’s spiced. It’s a full-on comfort food love letter from Greece—layered with silky béchamel, cinnamon-kissed meat sauce, and pasta that holds it all together like a warm fall hug.

This dish is made for when the temps drop and you’re ready to embrace cozy fall meals that feel like a celebration. Whether you’re cooking for family, meal-prepping for the week, or just want to hibernate with leftovers, this is the kind of meal that checks all the boxes.

What is Pastitsio, Anyway?

Think of Pastitsio as Greece’s answer to lasagna—but with a twist. Imagine:

  • Tubular pasta (like bucatini) lined up like little soldiers
  • A spiced meat sauce that tastes like autumn in a skillet (thanks, cinnamon!)
  • A thick, cheesy béchamel poured on top like a fluffy duvet

Yeah, we’re going full fall comfort dinner mode here.

Ingredients You’ll Need

For the Meat Sauce

  • 2 tablespoons olive oil
  • 2 pounds lean ground beef
  • 1 large red onion, chopped
  • 3 garlic cloves, minced
  • ½ cup red wine
  • 2 bay leaves
  • 1 teaspoon dried oregano
  • ¼ teaspoon ground cloves
  • ½ teaspoon ground cinnamon
  • 1 cinnamon stick
  • ¼ teaspoon allspice
  • Salt and pepper, to taste
  • 2 tablespoons tomato paste
  • 28 ounces crushed tomatoes
  • 1 cup water
  • 1 tablespoon sugar

For the Béchamel Sauce

  • ½ cup unsalted butter
  • ½ cup all-purpose flour
  • 4½ cups 2% milk
  • Salt and pepper, to taste
  • ¼ teaspoon ground nutmeg
  • ¾ cup grated Kefalotyri cheese (or Parmesan)
  • 2 large eggs
  • 2 egg yolks

For the Pasta

  • 1 pound Pastitsio pasta (or bucatini)
  • ½ cup Kefalotyri cheese
  • 2 egg whites

For the Topping

  • 1 cup Kefalotyri cheese
Pastitsio – Greek Lasagna

How to Make Pastitsio Like a Greek Yiayia

Step 1: Build the Meat Sauce

Heat olive oil in a large skillet over medium-high heat. Add the beef and cook for 10–15 minutes, breaking it up as it browns.

Stir in chopped onion and cook until soft and translucent, about 3–4 minutes. Add garlic and cook another minute.

Deglaze the pan with red wine. Add bay leaves, oregano, ground cloves, cinnamon, cinnamon stick, allspice, salt, pepper, tomato paste, crushed tomatoes, water, and sugar. Stir well.

Bring to a boil, then reduce heat to low and let it simmer, covered, for about 45 minutes. Stir occasionally. When thickened, remove bay leaves and cinnamon stick.

Pastitsio – Greek Lasagna (1)

Step 2: Cook the Pasta

While the sauce simmers, cook the pasta according to package instructions. Aim for al dente. Drain, let cool, and toss with a bit of olive oil.

Step 3: Make the Béchamel

Melt butter in a saucepan over medium heat. Whisk in flour and cook for 2–3 minutes.

Gradually whisk in the milk, followed by nutmeg, salt, and pepper. Cook for 5 minutes, whisking often, until thick and smooth. Remove from heat and stir in the cheese.

In a separate bowl, whisk eggs and yolks. Slowly add a ladle of hot béchamel to the eggs while whisking constantly to temper. Add a second ladle, whisk again, then pour the egg mixture back into the sauce, stirring briskly.

Step 4: Assemble the Dish

Preheat your oven to 350°F.

Grease a deep 9×13-inch baking dish with olive oil.

Toss the pasta with ½ cup meat sauce, egg whites, and ½ cup of cheese. Spread evenly in the baking dish, arranging the pasta mostly in the same direction.

Pour the remaining meat sauce over the pasta. Smooth it out.

Top everything with the béchamel and spread it into an even layer. Sprinkle the remaining cup of cheese on top.

Step 5: Bake

Bake uncovered for 45–50 minutes, or until the top is golden and set.

Let it rest at least 30 minutes before slicing so the layers stay intact. It’s worth the wait.

Why This is One of the Best Fall Comfort Food Recipes Around

If you love dishes that feel like a warm blanket and taste like fall, this is it. The spices—especially cinnamon and cloves—bring such cozy, unexpected depth. The creamy béchamel is downright dreamy. And the fact that it feeds a crowd? That’s a serious win.

Want more soul-soothing dinner inspiration? You’ll probably love these too:

How to Store It

Let it cool completely, then slice and store in an airtight container in the fridge for up to 4 days. Reheat in the microwave or oven.

It also freezes beautifully—just wrap slices individually and pop them in a freezer bag. You’ll thank yourself later.

Just One More Thing Before You Go

If you love collecting cozy meals, fall baking projects, and weekend dinner inspiration, you’ll find tons of ideas (and delicious eye candy) on our Pinterest page. Follow along for even more comfort food goodness, one pin at a time.

Pastitsio (Greek Lasagna) – The Ultimate Fall Comfort Dinner
Pastitsio (Greek Lasagna) – The Ultimate Fall Comfort Dinner
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Pastitsio (Greek Lasagna): The Ultimate Cozy Fall Dinner You’ll Keep Craving

greek-Lasagna

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Pastitsio (Greek Lasagna) is comfort food at its finest, layers of pasta, a rich, spiced meat sauce with red wine and cinnamon, and a thick, cheesy béchamel that’s baked to golden perfection. It’s a little effort, a lot of flavor, and exactly what you want when you’re feeding a crowd (or just want killer leftovers).

  • Author: Callie
  • Prep Time: 30 minutes
  • Cook Time: 2 hours 10 minutes
  • Total Time: 2 hours 40 minutes
  • Yield: 16 servings 1x
  • Category: Dinner
  • Method: Baking
  • Cuisine: Greek

Ingredients

Scale
  • 2 tablespoons olive oil
  • 2 pounds lean ground beef
  • 1 large red onion (chopped)
  • 3 cloves garlic (minced)
  • ½ cup red wine
  • 2 bay leaves
  • 1 teaspoon dried oregano (Greek or Mediterranean)
  • ¼ teaspoon ground cloves
  • ½ teaspoon ground cinnamon
  • 1 stick cinnamon
  • ¼ teaspoon allspice
  • Salt and pepper (to taste)
  • 2 tablespoons tomato paste
  • 28 ounce crushed tomatoes
  • 1 cup water
  • 1 tablespoon sugar
  • ½ cup butter (unsalted)
  • ½ cup all-purpose flour
  • 4½ cups 2% milk
  • Salt and pepper (to taste)
  • ¼ teaspoon ground nutmeg
  • ¾ cup Kefalotyri Greek cheese (or Parmesan, grated)
  • 2 large eggs
  • 2 egg yolks (reserve egg whites for pasta)
  • 1 pound Pastitsio pasta (or bucatini)
  • ½ cup Kefalotyri Greek cheese
  • 2 egg whites
  • 1 cup Kefalotyri Greek cheese (for topping)

Instructions

  1. Brown the meat: Add olive oil to a large skillet and heat over medium-high. Add beef and cook 10–15 minutes, breaking it up until browned.
  2. Cook onion and garlic: Add onion and cook 3–4 minutes until soft. Stir in garlic.
  3. Deglaze and simmer: Add red wine, bay leaves, oregano, cloves, cinnamon, allspice, salt, pepper, tomato paste, crushed tomatoes, water, and sugar. Bring to a boil, then simmer covered for 45 minutes. Remove bay leaves and cinnamon stick.
  4. Cook pasta: Boil pasta as per package instructions until al dente. Drain and let cool.
  5. Make bechamel: Melt butter in a saucepan. Whisk in flour for 2–3 minutes. Add milk, nutmeg, salt, and pepper. Cook 5 minutes, whisking. Stir in ¾ cup cheese.
  6. Combine eggs: In a bowl, whisk eggs and yolks. Temper with a ladle of bechamel, whisk, then add another ladle. Mix into the full bechamel sauce.
  7. Preheat oven to 350°F. Grease a 9×13-inch pan (3-inch deep).
  8. Prepare pasta: Toss pasta with ½ cup meat sauce, whisked egg whites, and ½ cup cheese. Add to prepared pan.
  9. Layer: Spread remaining meat sauce over pasta. Top with bechamel sauce and smooth. Sprinkle with 1 cup cheese.
  10. Bake 45–50 minutes until golden brown and set.
  11. Rest 30 minutes before slicing and serving.

Notes

Use lean ground beef to avoid excess grease. Substitute Kefalotyri cheese with Parmesan if needed. Let the dish cool 30 minutes before slicing. Store leftovers in fridge for 3-4 days. Freeze portions in airtight containers after cooling. Thaw overnight before reheating. Serve with a Greek salad.

Nutrition

  • Serving Size: 1 serving
  • Calories: 410
  • Sugar: 8g
  • Sodium: 394mg
  • Fat: 18g
  • Saturated Fat: 9g
  • Unsaturated Fat: 7g
  • Trans Fat: 1g
  • Carbohydrates: 34g
  • Fiber: 2g
  • Protein: 26g
  • Cholesterol: 114mg

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